Objective
\nTo determine the efficacy of prolotherapy for refractory rotator cuff disease.\n
Design
\nRetrospective case-control study\n
Setting
\nUniversity-affiliated tertiary-care hospital.\n
Participants
\nOne hundred fifty-one patients with non-traumatic refractory rotator cuff disease that was unresponsive to 3 month-long aggressive conservative treatments. Sixty-three patients received prolotherapies with 16.5% dextrose 10 ml solution (treatment group), and 63 continued conservative treatment (control group).
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