Platelet-Rich Plasma, Hydroxyapatite and Chitosan in the Bone and Cartilaginous Regeneration of Femoral Trochlea in Rabbits: Clinical, Radiographic and Histomorphometric Evaluations

Platelet-Rich Plasma, Hydroxyapatite and Chitosan in the Bone and Cartilaginous Regeneration of Femoral Trochlea in Rabbits: Clinical, Radiographic and Histomorphometric Evaluations

Introduction

Cartilaginous tissue is mainly present in the joints, and it consists predominantly of type II collagen and glycoproteins, which promote the tissue functions of supporting biomechanical forces, such as tension and compression, generated during the process of ambulation. The articular cartilage has a very limited regenerating or healing capacity in lesions with no involvement of the subchondral bone, resulting in an empty lacuna. This characteristic of the tissue causes traumas or degenerative diseases in this region, which are difficult to solve.

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