Introduction
The use of platelet concentrates is becoming very popular in the field ofmusculoskeletal tissue regeneration.Awidespread interest has been shown for platelet-rich plasma (PRP) as an injective treatment or as a surgical augmentation procedure of several tissues [7]. These molecules bind to the transmembrane receptors of their target cells regulating cell signaling pathways [1, 7, 8]. Alpha-granules also contain cytokines, chemokines, and many other bioactive proteins that stimulate chemotaxis, cell proliferation, and maturation, modulate inflammatory molecules, and attract leukocytes [8].
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