Abstract
Purpose: The aim of the study was to investigate the effects of platelet rich fibrin (PRF) and plasma rich in growth factors (PRGF) on the injured peripheral nerve in the early period of healing.
Results: Regarding electrophysiological evaluation, both the latency and amplitude values in D, PRF and PRGF groups were significantly lower than the C group (p> 0,05). According to the SFI result, there were significant differences between the groups D and PRF, D and PRGF (p = 0,000). As a result of stereological evaluations, while no significant difference observed between PRGF and C groups (p> 0,05), significant difference observed between D, PRF and PRGF groups in terms of myelinated axon number. There were significant differences between the groups D and PRF, D and PRGF in terms of the axon area (p = 0.021), (p = 0.001) respectively. No significant difference observed between D, PRF, and PRGF groups in terms of myelin sheath thickness and axon area/myelin sheath thickness ratio (p> 0.05).