Autologous Platelet-Rich Plasma Preparations - Influence of Nonsteroidal Anti-inflammatory Drugs on Platelet Function

Autologous Platelet-Rich Plasma Preparations - Influence of Nonsteroidal Anti-inflammatory Drugs on Platelet Function

Abstract

Background Autologous platelet-rich plasma (PRP) has been widely used for the treatment of sports injuries. It has been associated with improved healing and regeneration of soft tissues in elite athletes. Athletes are commonly receiving nonsteroidal anti-inflammatory drugs (NSAIDs). As yet, the effect of these drugs on platelet function in PRP formulations has not been taken into consideration.

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Hypothesis The function of platelets in PRP produced under the influence of NSAIDs is inhibited and may lessen a possible healing effect on the site of injury.

Study Design Controlled laboratory study.

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